All conditions
BPC-157 for knee

Knee Pain General

Of the 74 unique stories with a clear outcome, 65 reported it helped (88%). 6 were inconclusive.

These are public YouTube testimonials, not clinical evidence. People who tried BPC-157 and got no result rarely post videos — read this as a sample of the positive end of the distribution.

Verdict
88
% positive
59 helped6 partial9 no help6 unclear
What people tried
500-1000 micrograms, oral BPC-157 injections in the knees injected BPC-157 straight into the joint intra-articular injection
Source
YouTubeHelped · mild500-1000 micrograms, oral
I feel more stable and a little bit more rigid
Quote at 3:10
YouTubeHelped · significantBPC-157 injections in the knees
11 of the 12 reported significant knee pain reduction
Quote at 13:33
YouTubeHelped · significantinjected BPC-157 straight into the joint
massive reduction in knee pain
YouTubeHelped · mildintra-articular injection
reported there was subjective... 'Yeah, I feel better.' in many patients
Quote at 7:15
YouTubeHelped · significantintra-articular injection, 10-20mg
most of the patients did actually say that they felt better
Quote at 5:21
YouTubeHelped · significant250 micrograms of BPC three times a day, 500 micrograms of TB500 every other day
BPC and TB500 for my rats... to help my knees be able to squat
YouTubeHelped · significantBPC-157 injectionsover 52 weeks
11 out of 12 people said they were doing better
Quote at 0:57
YouTubeHelped · completeBPC-157over 1 week
I had full range of motion in one week
Quote at 3:10
YouTubeHelped · significantinjected into the knee
87-ish percent of the patients had significant pain improvement
Quote at 2:58
YouTubeHelped · significantintra-articular injection by a doctor
pretty impressive, the pain relief that they reported
Quote at 7:10
YouTubeHelped · significantintra-articular knee injectionsover 24 weeks
14 of 16 supported or reported significant pain relief lasting six months or longer
Quote at 1:48
YouTubeHelped · significantBPC-157 and TB-500, exact dosage and frequency not specifiedover at least 26 weeks
most of my days, I don't think about the pain that much
YouTube comment
@puppiesandhorsepower
It healed my knee injures and my chronic back pain is better. It also SAVED MY DOGS LIFE I made a quick video so all dog owners are away of how it can help their dogs https://youtu.be/yI3DP8eFDMw?si=LHq-_LgJtWCQGYlR
YouTube commentHelped · complete
It healed my knee injures
@puppiesandhorsepower·Youtube CommenterSource ↗
YouTube comment
@puppiesandhorsepower
Healed my knees and back and SAVED my dogs life. I made a quick video so all dog owners know about this !! https://youtu.be/yI3DP8eFDMw?si=LHq-_LgJtWCQGYlR
YouTube commentHelped · complete
Healed my knees
@puppiesandhorsepower·Youtube CommenterSource ↗
YouTube comment
@puppiesandhorsepower
It healed my knees and helped my back injury. It also SAVED MY DOGS LIFE I made a video as I feel it’s so important everyone know this for dog ownership. https://youtu.be/yI3DP8eFDMw?si=LHq-_LgJtWCQGYlR
YouTube commentHelped · complete
It healed my knees
@puppiesandhorsepower·Youtube CommenterSource ↗
YouTube comment
@عبدالرحمن_تركي13
يقدم هذا الفيديو تجربة شخصية لأحد المستخدمين الذين جربوا ببتيد BPC-157 عن طريق الفم لمدة 6 أشهر، وهو ما يعزز النقاط التي ناقشناها حول استخدامه في أوساط الرياضيين والاستشفاء البدني. ​إليك أبرز النقاط التي استعرضها صاحب التجربة في الفيديو: ​1. الفعالية في علاج الإصابات المزمنة ​ذكر صاحب الفيديو أنه كان يعاني من التهاب الأوتار المزمن في عضلة البايسبس (Bicep Tendonitis) بسبب التمارين الثقيلة، بالإضافة إلى مشاكل في الركبة [01:39]. ​لاحظ تحسناً ملموساً بعد حوالي 10 أيام فقط من البدء، حيث اختفى الشعور بالنبض والضغط الناتج عن الإجهاد في تلك المناطق [01:50]. ​2. الشكل الصيدلاني (فموي vs حقن) ​أشار إلى أن الكبسولات الفموية تكون أكثر فاعلية لمشاكل الجهاز الهضمي (الأمعاء) [00:22]. ​بينما يرى أن الحقن الموضعي عادة ما يكون أكثر فعالية في حالات التئام الجروح وإصابات المفاصل المحددة مثل الركبة أو الورك [00:30]. ​3. الجرعات والآثار الجانبية ​استخدم جرعات تتراوح بين 500 إلى 1400 ميكروغرام يومياً (موزعة على الصباح وقبل النوم) [02:48]. ​لم يلاحظ أي آثار جانبية سلبية خلال فترة الستة أشهر، وأكد أنه حتى بعد التوقف عن استخدامه لستة أسابيع، لم تعد آلام الأوتار إليه، مما يشير إلى حدوث "ترميم حقيقي" وليس مجرد تسكين مؤقت [03:03]. ​4. آلية العمل المقترحة ​يرى صاحب التجربة أن المادة تعمل عبر فتح الشعيرات الدموية حول مناطق الإصابة، مما يسمح بتدفق المزيد من الأكسجين والدم، وهو ما يحتاجه الجسم لإصلاح الأنسجة بكفاءة [02:14]. ​5. الوضع القانوني والتكلفة ​أكد أن المادة لا تزال تعتبر "مادة بحثية" ولم تعتمدها هيئة الغذاء والدواء الأمريكية (FDA) للاستخدام البشري الرسمي بعد [00:54]. ​وصف المنتج بأنه مكلف، حيث يبلغ سعر العبوة (تكفي لستين يوماً) حوالي 130 إلى 140 دولاراً [01:16]. ​ملاحظة ختامية: يوضح الفيديو أن هذا الببتيد يمنح شعوراً يشبه "قدرات ولفرين" (Wolverine) في سرعة الاستشفاء والمرونة [03:13]، ولكنه يشدد في النهاية على أن هذه ليست نصيحة طبية بل مجرد مشاركة لتجربة شخصية. ​يمكنك مشاهدة الفيديو كاملاً عبر الرابط: Oral BPC 157 Results After 6 Months
YouTube commentHelped · significant500-1400mcg/day, oralover 24 weeks
لاحظ تحسناً ملموساً
@عبدالرحمن_تركي13·Youtube CommenterSource ↗
YouTube comment
@markbrackenhoff1676
BPC-157 isn't sold/controlled by big pharma, so watch carefully as big med/pharma try to demonize it. "Lack of human studies..." They will probably never have a human study on this peptide because it would instantly prove how effective it is. I've used BPC-157 as a recovery tool from shoulder and knee pain due to hard lifting and sprint workouts - it's insanely effective. I'm 58 and didn't think it was possible for me to recover like this.
YouTube commentHelped · significant
it's insanely effective
@markbrackenhoff1676·Youtube CommenterSource ↗
YouTube comment
@jimwhite695
BPC-157 made my knee pain and foot pain go away. My bad bicep injury pain went down about 50%, I plan to try another 30 days with pill form hoping bicep pain goes down more.
YouTube commentHelped · complete
BPC-157 made my knee pain... go away
@jimwhite695·Youtube CommenterSource ↗
YouTube comment
@JimFriedman-f1n
I used BPC-157 from life link after getting stomach problems, took me like 3 weeks to notice my gut wasn’t acting up much. Glad you bring up joints too, cause i think it helped my knees from all the running. Keep sharing more about recovery, real helpful info.
YouTube commentHelped · mild
helped my knees
@JimFriedman-f1n·Youtube CommenterSource ↗
YouTube comment
@joannrussell6004
I have both knee joint pain with torn cartilage, since taking this I feel AMAZING no more pain and I can ACTUALLY walk normal now , I've been taking this for 3weeks and WHAT A RELIEF FROM LIVING IN PAIN , I'm a 50 years old lady and I'm glad I found this .
YouTube commentHelped · completeover 3 weeks
no more pain and I can ACTUALLY walk normal now
@joannrussell6004·Youtube CommenterSource ↗
YouTube comment
@idontwantahandle510
Prp fixed my knee, stem cells fixed my shoulder and other knee. Im trying bpc 157 right now for tears in my tricep tendons. Once I get better I swear this time I'm not going to lift heavy again.
YouTube commentHelped · completeprp
Prp fixed my knee
@idontwantahandle510·Youtube CommenterSource ↗
YouTube comment
@wm7102
My sister in law did prp for her knee & it worked Great. This was a couple of years ago & she's still good to go / much better. This was done in Ecuador btw. Love the videos - Thanks Doc. God bless all. 🙏 Peace
YouTube commentHelped · complete
worked Great
@wm7102·Youtube CommenterSource ↗
YouTube comment
@artandersen7358
You keep saying we just don’t know. Also, you keep saying that there is no data on this. Those two statements are not true. Well, there may be no scientific studies. There are real world effects that tens of thousand people are reporting. I myself have had 11 surgeries on my right knee. On the ninth surgery, my doctor was insistent that we amputate the leg. I had asked him about several different peptides around the sixth surgery and as you have said, he would not even talk about him because there were no FDA studies. So with that during the 10th surgery where they removed the steel from my knee once again for the fifth time I started to take peptides three of them were the 500, 157 and the additional copper blend that works them together. My right leg for the last 2 1/2 years had been double the size of my left leg before after enduring surgeries. But the fifth day of taking these, I woke up and looked in the mirror. Both my legs looked exactly the same for the first time in almost 3 years. We move forward with my 11th surgery, placing another knee replacement and for the first time it worked. It has now been six months and I feel terrific. There was no imagining that this happened. It truly did happen and saved my right leg. People like you can call me a wrapped lab, but these things truly work. I would truly recommend to anyone having major surgery to use these peptides. They have absolutely saved my life. I do not want to drag this out too long as I can talk about other effects from peptides that I have taken. What I will say is that I am leaner happier sleep better and I’m stronger at 55 than I was at 45. For the first time in my life, I have a true six pack in my abdominal area. I realize these are not a fountain of youth medication, but they do create incredible results. This has just been my journey and I am not trying to state that anything you’re saying is wrong. I am just stating to you that I know how I feel and when I look in the mirror and see the incredible results I cannot deny the effectiveness of them. My entire world has changed in the last three months.
YouTube commentHelped · completeBPC-157 and copper blendover 6 weeks
My right leg for the last 2 1/2 years had been double the size of my left leg... Both my legs looked exactly the same
@artandersen7358·Youtube CommenterSource ↗
YouTube comment
@thssportingcenter1
Seriously I need BPC157! Pain management being roughly 30% less pain medication. 59 years old. Both knees operated, lower back operation and right shoulder twice. Jfyi not fat being 6'0" 177# fairly active (slow pace) . If I don't use BPC157 in a few days the discomfort increases. Considering TD500 and GHK-CU for a break from BPC157. This is all information from a parallel universe that has nothing to do with me. Just the guy in that universe is great at communicating with me. 😅
YouTube commentHelped · significant
Pain management being roughly 30% less pain medication
@thssportingcenter1·Youtube CommenterSource ↗
YouTube comment
@Attorney57
For what it helps, as a regular guy, I workout and play golf a lot. A good friend told me the knee and elbow pain he's had for about two years finally went away after taking BP-157, and having changed nothing else. After he recommended it, I started it and have been using it for approximately two weeks. What's surprised me is how much better I feel the morning after a long day of golf or working out. The soreness, stiffness, and fatigue has dropped by about 90% and, frankly, I'm shocked. I've changed nothing else. My takeaway is that it's helping my body recover much more quickly and I'm not sure how. The second more minor takeaway is that the light pain on the front of my right shoulder I used to get while bench pressing has diminished. It's not gone, but I wonder if it'll go away completely once I've taken this for more than only a few weeks. Guess we'll see, but so far, I'm very impressed.
YouTube commentHelped · complete
knee and elbow pain he's had for about two years finally went away
@Attorney57·Youtube CommenterSource ↗
YouTube comment
@WhiskeyJack200
I'm currently using BPC 157 and TB 500. I have epilepsy and have ruined my knees. I used to love hiking and biking but stopped a year ago (17 years since diagnoses.) On top of this, I screwed my back on a poor form deadlift 2 months ago. I started the cycle 1.5 weeks ago. Knee pain is gone. Shoulder pain from constant manual labor, gone. Back pain about 70% gone. (I still have soreness, but no longer wake up feeling like a pile of welded scrap metal.
YouTube commentHelped · completeover 0.25 weeks
Knee pain is gone
@WhiskeyJack200·Youtube CommenterSource ↗
YouTube comment
@rumble5557
If youre an athlete finding this video for shoulder issue I can say it truly works. Im 2 and a half weeks in and ive seen a dramatic difference. Im taking the oral route. Also my left knee was bothering me too and thats cut down 80%. Definetelt a believer. Zero side affects which is a big deal for me. My body is sensitive and prone to anxiety. Zero issues. Good luck! Im a crossfitter, body builder and very active on my property in Tennessee.
YouTube commentHelped · significantoral routeover 2.5 weeks
that's cut down 80%
@rumble5557·Youtube CommenterSource ↗
YouTube comment
@Burdette305
1 vial of KLOW did a miracle on my knee pain. Used it in December and it's still holding up now. I jogged a mile the other day and felt no pain still.
YouTube commentHelped · complete1 vial
1 vial of KLOW did a miracle on my knee pain
@Burdette305·Youtube CommenterSource ↗
YouTube comment
@TheRedGunn
Only the injections worked for me personally, pertaining to resistance training knee injuries. Oral form did nothing at all. Injections directly to the knee worked wonders
YouTube commentHelped · significantinjections directly to the knee
Injections directly to the knee worked wonders
@TheRedGunn·Youtube CommenterSource ↗
YouTube comment
@TheSheila4444
I am living proof and I’m living proof that exosomes work and all because of Dr. Greir. I had 3 knee surgeries and three ortho said I had to have shoulder surgery, but I decided to try exosomes prp and peptides and here I am three years later, my knees are healed my shoulders halfway there and my L4 L5 is doing pretty dang good all things considered. It’s bone bone and that’s just from using BPC with TV 500.
YouTube commentHelped · completeBPC with TV 500over 156 weeks
my knees are healed
@TheSheila4444·Youtube CommenterSource ↗
YouTube comment
@johnz.2907
I see there's different brands with better/worse purity. Im taking oral capsules, feeling better but raises blood pressure. Def eat with it. Im a 47 year old remodeling contractor. So shoulders tore, knees crackling, lower back pain, sciatica, tendonitis in my right hamstring. Headaches come when you take too much from BP going up.
YouTube commentHelped · mildoral capsules
feeling better
@johnz.2907·Youtube CommenterSource ↗
YouTube comment
@jimwhite695
This guy is so FOS, long painful foot problem and bad knees, by the beginning of my fourth week pain gone. The Ultimate Human on YouTube has many good experts on BPC-157. This guy must be hoping to get some big pharma kick back, he is wrong.
YouTube commentHelped · completeover 4 weeks
bad knees... pain gone
@jimwhite695·Youtube CommenterSource ↗
YouTube comment
@Soxfandan
Appreciate the fact you are responding to people so I will add my own experience. I'm 47 years old and in muay thai kickboxing, also was doing some coaching youth soccer. In late May of '25 sprained my ankle playing soccer with the kids. Didn't feel right at the gym so I took about 5 weeks off. Went back for a month (mid-July through mid-Aug) and in that time injured my knee slamming it down in a take-down drill in martial arts. At this point (Aug 25th) when they weren't healing as fast as expected went to see the orthopedic specialists. They shot it up with cortisol and said come back in a month. Other than said the X-Rays were fine and the ankle guy ordered an MRI, the knee guy said gave me a prescription for some anti-inflammatories (4 days later I am still waiting for the pharmacy to tell me they are ready). While this was going on I asked my buddy who is a pro mma fighter what he did for his knees which were messed up bad months ago (a friend of his who is a well known, pro fighter hooked him up with a UFC doctor who said they were some of the worst knees he's ever seen). He told me about BPC-157 and how much it helped. Another mutual friend said the same, so I tried their connection. After about 6 days and 3 doses (.3 mL every 3 days), my knee feels better than it has in months. Much better than any of the traditional stuff being done. I think there is a problem in a severe lack of trust in the FDA (and large segments of the medial industry) in regards to their profit motives. They approve absolute poison in our foods (as much as I tend to not like over regulation, having lived in Europe 4 years I appreciate what they don't allow to be put into food), meanwhile they seem to suppress cheaper and easier medical options to push big pharma options. They don't seem to want people on something like hydroxychloroquine when there are more profitable "vaccines" to sell you, and don't seem to want people on something like petides when there are much more profitable surgeries to sell you on. The lack of studies seems highly suspect when we are in a world where we are forced to hear about trans everything every 10 minutes (when that affects a tiny number of people), but they seem to be in no rush to look into this stuff, when they could have had some answers on this half a decade ago. I agree you need more than some anecdotal stories (from my research there seem to be thousands), but people have just lost trust in the authority figures... so seeing a lot of examples of it working (esp to those they trust) starts meaning more than the piece of paper on the wall at a certain point. Thank you for you time.
YouTube commentHelped · significant.3 mL every 3 daysover 0.4 weeks
my knee feels better than it has in months
@Soxfandan·Youtube CommenterSource ↗
YouTube comment
@AmberFord-c6f9f
appreciate the honest talk on the difference between oral and injectable, i always get confused on what's better. started with oral bpc157 from life link peptides, did okay for gut stuff but injectable from them helped me recover my knee a lot faster somehow. thanks for clearing up some of that info, really.
YouTube commentHelped · significantinjectable
helped me recover my knee a lot faster
@AmberFord-c6f9f·Youtube CommenterSource ↗
YouTube comment
@TJ-lz9jv
I started injecting Bpc 157 for a knee problem i have had for years. Month later taking bpc 157 no more problems completely healed. This stuff is no joke it's amazing!
YouTube commentHelped · completeover 4 weeks
no more problems completely healed
@TJ-lz9jv·Youtube CommenterSource ↗
YouTube comment
@itstopic7973
I had a bad knee for about 3 years. It was so bad that at 1 point i stopped completely doing leg day. Chiropractor couldn’t fix it. Nothing bad in xrays. Took BPC157 (subcutaneous) and in matter of a few days the pain just went away.
YouTube commentHelped · completesubcutaneous
pain just went away
@itstopic7973·Youtube CommenterSource ↗
YouTube comment
@miningpro2798
Been on peptides for a week now wolverine I hurt both knees a while back and it feels like i never hurt it anymore peptides are real
YouTube commentHelped · completeover 1 week
it feels like i never hurt it anymore
@miningpro2798·Youtube CommenterSource ↗
YouTube comment
@compoundhq1
This is exactly the kind of content I've been searching for! I started a BPC-157 and TB-500 protocol about 3 months ago after struggling with gut inflammation and an old knee injury, and the difference has been remarkable. Learning about GHK-Cu and KPV here just made me want to add the full glow stack - Dr. Froese explains everything so clearly without the intimidating jargon. I actually sent this to my functional medicine doctor right away. Thank you so much for this!
YouTube commentHelped · remarkableBPC-157 and TB-500 protocolover 12 weeks
the difference has been remarkable
@compoundhq1·Youtube CommenterSource ↗
YouTube comment
@justinchambers6257
I did BPC-157 and CJC-ipam! They definitely do stuff and CJC definitely makes you flush and tingle in the hands and it is good if it does that! If not you got fake peptide! No flushing it’s fake most likely! CJC nice but the BPC did the most as I tore something in my knees orthopedic said the edge of my rotator maybe meniscus I could barely walk. I took BPC 1 month and it healed it enough where I could start walking and doing stuff again! It’s actually nuts! It’s been about two or three months since I stopped my knee still pretty bad. I’m gonna try another month of it to see if it heals it even more. Will let you guys know! After!
YouTube commentHelped · significant1 monthover 4 weeks
I took BPC 1 month and it healed it enough where I could start walking
@justinchambers6257·Youtube CommenterSource ↗
YouTube comment
@Pussywagonriders
Bpc-157 and tm500 has helped me dramatically so far. I had knee and joint pain for years now and my left knee would give out all the time. I started to use bpc-157 and tm500 and three days later no pain not only in left but also in right. Absolutely amazing however it’s only been a week. I look forward to seeing if it healed my issues or covered them while in my system or cycle.
YouTube commentHelped · completebpc-157 and tm500over 0.14 weeks
no pain not only in left but also in right
@Pussywagonriders·Youtube CommenterSource ↗
YouTube comment
@jrgomez8133
I’ve started bpc-157 & tb500 on my third week now and I’ve felt so much improvement on some of my nagging injuries. (Bicep tendonitis, two knee injuries). Can’t say yet if it’s helped me mentally in anyway. Should someone cycle BPC?
YouTube commentHelped · significantover 3 weeks
felt so much improvement on some of my nagging injuries. (two knee injuries)
@jrgomez8133·Youtube CommenterSource ↗
YouTube comment
@welderdude1
My healing process from my distal bicep tendon rupture surgery has been cut in half. I also tore my left knee last November and was unable to kneel. Both of my knees feel great now. I am being very careful with my physical therapy as the hole in my bone from the bicep surgery still has to heal completely. I have an extremely physical job and have been able to return to work in just 2 months from surgery. I don't have the same problems I had when my other arm suffered the same injury. That was a full year to get where I am now just 90 days post surgery.
YouTube commentHelped · complete
Both of my knees feel great now
@welderdude1·Youtube CommenterSource ↗
YouTube comment
@SteveMorring
I used 500 mcg of BPC and 1000 mcg of TB 500 directly to my knee which has been filled with fluid and pain behind the knee this morning and within a few hours the fluid in my knee was gone
YouTube commentHelped · complete500 mcg of BPC and 1000 mcg of TB 500 directly to the knee
fluid in my knee was gone
@SteveMorring·Youtube CommenterSource ↗
YouTube comment
@MoeSharrif
You really can't go wrong with BPC157. I tried this peptide while I was healing from a knee injury after a bike fall, and it made a huge difference in my recovery. Plus, if you combine it with TB500 from Swisschems, it boosts the healing effects even more.
YouTube commentHelped · significantcombined with TB500
made a huge difference in my recovery
@MoeSharrif·Youtube CommenterSource ↗
YouTube comment
@waynesullivan7825
Been taking BPC 157 for 3 weeks for old knee injury that flared in 2019. I was unable to run 2 months ago and standing/walking was becoming an issue. Standing/walking no longer a problem and I'm on the treadmill for now with no issues s.
YouTube commentHelped · significantover 3 weeks
Standing/walking no longer a problem and I'm on the treadmill
@waynesullivan7825·Youtube CommenterSource ↗
YouTube comment
@gtharo
I did BPC-157 for a month to help my bad knees from years of heavy squatting and overall wear and tear. I’m happy to report, my knee issues are gone. I’m back to squatting and doing leg presses; albeit light weight with no discomfort. I co-sign BPC-157 for its effectiveness!
YouTube commentHelped · completeover 4 weeks
my knee issues are gone
@gtharo·Youtube CommenterSource ↗
YouTube comment
@gebhardts1638
I had bad knee pain for the past year. Felt a little pop right next to my right knee cap when I squatted down one day caused the pain. Very painful to do leg workouts anytime quads involved. 3 months on 500mcg per day and now my knee is at LEAST 95% better! Absolutely amazing! Also fixed a long lingering rotor cuff pain. This shits legit.
YouTube commentHelped · significant500mcg per dayover 12 weeks
knee is at LEAST 95% better
@gebhardts1638·Youtube CommenterSource ↗
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@nunninkav
My research shows good results using 500mcg of BPC-157 EOD at night, IM. 2 year lingering knee injury gone away, horrible shoulders are no longer popping and tricky. 100mcg of Thymosin beta 4 sent into brief tachycardia.
YouTube commentHelped · complete500mcg EOD IM
2 year lingering knee injury gone away
@nunninkav·Youtube CommenterSource ↗
YouTube comment
@ianscreams
Local doesn’t have to mean deep into the damaged tissue. It can simply be local subq. The closer to the target area you can get the better because a higher concentration will hit it, as it absorbs and spreads, rather than if you inject far away. Sort of pseudo logic but still fairly logical. I had luck w alleviating knee issues by doing bpc in the the flesh around my knee. More immediate and observed response than into the belly.
YouTube commentHelped · significantlocal subq injection around the knee
had luck w alleviating knee issues
@ianscreams·Youtube CommenterSource ↗
YouTube comment
@cobrairish1945
Hi I have lower chronic back pain. About two weeks ago I a medial branch block conducted on my lower back. I can’t say for sure if it decreased the pain. But my pain in the back of my knees really decreased! Anyways I had the Radial Frequency Abliation done today. Anyways where is your medical office located? I live in Southern California
YouTube commentHelped · significantover 2 weeks
pain in the back of my knees really decreased
@cobrairish1945·Youtube CommenterSource ↗
YouTube comment
@KetovoreRobert
people in their 70's need some sort of help.... my mom is 77,, her knee pain just started, 5 days of bpc157.. she stands up no pain............. yeah it works.......... .5 mcg
YouTube commentHelped · complete.5 mcg
knee pain just started, 5 days of bpc157.. she stands up no pain
@KetovoreRobert·Youtube CommenterSource ↗
YouTube comment
@mattjagger4360
I took BPC 157 after some chronic tendonitis and a painful knee and rotator cuff. Basically...i was falling apart ag 41 i felt like and moved like a 70yr old. I took 1 full bottle...lasted 30 days. Felt changes within 2 weeks. And over the next 2 months...healed. i mean. Healed. I have no tendon pain. My rotator cuff injury...gone. knee pain...what knee pain. Honestly chsnged my life.
YouTube commentHelped · complete1 full bottle, 30 daysover 2 weeks
knee pain...what knee pain
@mattjagger4360·Youtube CommenterSource ↗
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@LeonardoCubillos-f8i
I ran the Wolverine stack systematically in the morning and took BPC-157 at night, 250 mcg in each knee (1 mg total per day). It didn’t seem to help me. After running some tests—which showed no major issues—my orthopedic did a single injection of hyaluronic acid in each knee last week. I’m still resting, but my knees felt significantly better the next day. My knee issues were mostly from running
YouTube commentHelped · significantsingle injection of hyaluronic acid
My knees felt significantly better the next day
@LeonardoCubillos-f8i·Youtube CommenterSource ↗
YouTube comment
@حسينعلي-و9ر1ص
my BPC-157 protocol from gomitrox resolved a chronic knee injury that had not responded to anything else
YouTube commentHelped · completeBPC-157 protocol from gomitrox
resolved a chronic knee injury
@حسينعلي-و9ر1ص·Youtube CommenterSource ↗
r/Biohackers · Comment
@Desper84Inspir8ion
Every doctor told me that my knee would probably ache and give me pain every day for the rest of my life unless I had surgery, and even then it would not be at 100%…. I haven’t had any problems with it for the last year. BPC-157 and TB 4 are the GOAT!
Reddit comment · r/BiohackersHelped · completeover 52 weeks
I haven’t had any problems with it for the last year.
@Desper84Inspir8ion·Reddit UserSource ↗
r/Biohackers · Comment
@Ancient_Being1163
I have been using these 2 peptides for almost 3 weeks now and they are literally working wonders. I was given corticosteroids which took the pain away for 1 month and also hyaluronic acid which irritated my knee for a week and the doctor told me it couldn’t help. So I found someone else and they gave me 2 PRP injections which only helped very slightly and the second dose gave me a full body fever. Very bad. Then I remembered that during training a lot of people were talking about peptides like bpc and tb 500. I studied the first, the last, storage, handling, dosage, I take 250 mcg bpc morning and night and tb500 every other day for stability. I had mixed feelings but I have a great supplier with 3rd party testing. For this purpose I use collagen type 2 intended for cartilage, I make extra strong broths and take supplements such as: MSM EGG MEMBRANE VITAMIN D VITAMIN C I walk 10 km every other day. I am currently thinking about a peptide called Ghk-cu, although the articles say that it activates collagen type 1, which for my purposes is collagen type 2. In any case, I plan to extend the cycle to 6 weeks and then stop and assess the situation. If necessary, I will give my body the same time to restore the receptors as I will take it. And my question is. How did you feel after stopping? What did you give your body, whether in the form of supplementation or movement, exercises to restore receptor sensitivity? Or was it just time? By the way, for the first 6 days I had no side effects, slight lethargy, otherwise absolutely nothing. This is my personal experience so far. If anyone has any tips, please share them with me.
Reddit comment · r/BiohackersHelped · significant250 mcg BPC morning and nightover 3 weeks
they are literally working wonders
@Ancient_Being1163·Reddit UserSource ↗
r/Biohackers · Comment
@Injured_again
I think voodoo flossing and deep tissue massage would be worth trying I've had that constant soreness before - At my worst, I went 3 weeks unable to squat past 45 degrees without some kind of sore/tightness/pain feeling in my knee and quad tendon. And any kind of exercise just made it worse. Turns out my quads were just really really tight from exercise and were constantly pulling on my quad tendon/knee. The deep tissue massage (particularly cross-friction massage with a lacrosse ball) and voodoo flossing loosened up all my muscle and connective tissue and all my pain went away. I still do it every other day and have never felt better. I'm not sure if your issue is the same as mine, but I think it's a pretty easy thing to at least try! The voodoo flossing would cause immediate relief if tightness is the problem
Reddit comment · r/BiohackersHelped · completeover 3 weeks
all my pain went away
@Injured_again·Reddit UserSource ↗
r/Biohackers · Comment
@kennpacchii
I know people say “oral is only for gut health” but I’ve been having an issue with runners knee for the past month and it was not getting better at all. I also didn’t want to just stop running for a solid month or two until it healed and lose my progress. I took infiniwells oral BPC 157 and after about two weeks of taking it there has been zero pain in my knee and I noticed it no longer hurts after my long runs. The only delta in my regimen these past couple of weeks was the oral capsule I was taking 🤷‍♂️ anyways Infinwell is my go to for it.
Reddit comment · r/BiohackersHelped · completeoral capsuleover 2 weeks
zero pain in my knee
@kennpacchii·Reddit UserSource ↗
r/ChronicPain · Post
@bubbbalicious
Healing peptides cured my chronic pain. YMMV but worth a shot looking into
I had unexplained tendonosis wide spread thru out my body for many years. I suffered from overuse and most recently my hips were in so much in pain, it hurt to sit, stand, sleep, sex, I was pretty depressed I stopped going out because I didn’t want to be uncomfortable sitting on unknown chairs (all chairs hurt) and having to explain to people how I’m uncomfortable. Mri finally showed high hamstring tendonosis but along with that my elbows were suffering, my ankle was getting weak and I’ve been dealing with a knee injury for over a decade. The hip / hamstring was inflamed for over 2.5 years. March 2022 I started my first vial of bpc157 and tb500 (thymosin 4 fragment 17-23) from Canlabs. I used 1 vial of each per month. 55 days after starting I felt mild improvement but wasn’t sure. 3-4 months after starting I was in much better shape and could say the peptides were working. I wasn’t sure if this would be long lasting or not. Anyways that summer I twisted my knee because I was so excited to finally be able to use my leg so I was an idiot, so back on the peptides I went. I took them every other month until Dec 2022. I didn’t need to take them that long but i figured I had that much healing in 4 months, how much more healing will I get in another 4-5 months? Fast forward to today, I’ve been weight training for 8 months, I am fit; strong. Can do pull ups, weighted squats, I can run now! (I could never do these things before) and IM NOT IN PAIN. I can sleep in any position and do whatever I want. I just turned 35. This time around I can FEEL that I’m healed and the peptides gave me what I needed to permanently heal my body. (Side effects included a ravenous appetite from the BPC (had to start intermittent fasting) and TB5 worsened my anxiety and gave me nightmares so I had to take smaller doses in the morning only - it spikes cortisol apparently). I used a couple more vials of BPC than I did tb5 because of side effects. Maybe 7 bpc vials and 5 tb5. Every day I wake up grateful and I’m stoked I got my life back 😭😭😭😭😭😭😭 <<< tears of joy Just wanted to share hope this helps someone
Reddit · r/ChronicPainHelped · complete1 vial of BPC-157 and TB-500 per monthover 16 weeks
I can run now
@bubbbalicious·Reddit UserSource ↗
Quote at 1:50
YouTubeHelped partially · mildover 8 weeks
my joints were more tolerant of my exercise
YouTube comment
@wegoingplaces
I had a couple of PRP shots when I was in the military stationed in Korea. I was having issues with my knees, still do, and they sent me to the doctor to get a PRP shot appointment. They drew my blood from the knees I guess you can say they separated the blood from the plasma and then injected the plasma back in my knees. They did this process 2x. The worked but it was temporary. After every 2 months I had to repeat the process. The Doc eventually told me that it would be best that I a no longer run and started a no running profile which is basically saying that I am no longer authorized to run under any circumstances unless in a combat situation. Well needless to say I hung up the uniform 3 years later. I am eager to try out BPC-157 to see what the results would be on both knees.
YouTube commentHelped partially · mildPRP shotsover 8 weeks
The worked but it was temporary
@wegoingplaces·Youtube CommenterSource ↗
YouTube comment
@dimencia1970
I've been both for 2-weeks and my knee and hand pain has reduced from 100 to 60. Boy go do something with urself. How much are they paying you? Go get an implant
YouTube commentHelped partially · mildover 2 weeks
knee and hand pain has reduced from 100 to 60
@dimencia1970·Youtube CommenterSource ↗
r/Biohackers · Comment
@ObiWanKarlNobi
Oral BPC-157 helped my knee issues. Maybe. I don't know. Peptides are hit and miss. They are so poorly regulated that people saying "No, they didn't help" could have easily gotten a bad batch. I definitely noticed good things taking oral BPC-157 internally. I got mine from a brick and mortar independent supplement store so I think my source was good. The guy who ran the store told me to buy that specific brand over the other one he carried.
Reddit comment · r/BiohackersHelped partially · mildoral
Oral BPC-157 helped my knee issues. Maybe.
@ObiWanKarlNobi·Reddit UserSource ↗
r/Biohackers · Post
@Top_Buy2467
Hot, painful knees, no help from BPC-157, looking for suggestions
I’m 26M, former student athlete, trying to figure out the root cause of inflammation in my knees. My knees have had their fair share of use and abuse in my life, but even as I’ve tried to slow down the high impact usage, I can’t seem to find improvement. Both knees (but my right one more so) are constantly sore, and hot to the touch. I’ve sent multiple doctors about this, I’ve gotten sensitivity tests to foods done that didn’t reveal anything severe enough to pin as the cause. Went on BPC-157 for around 2 years (oral and injectable at the recommendation of my doctor), it definitely helped for a while, especially when taking after particularly intense exercise for recovery, but did not solve the baseline, day to day pain and inflammation. Due to life and family stuff, I haven’t had nearly as much time to exercise this last year, and my knees really haven’t gotten any better, and I’m not sure which direction to go now. Up until now, I think I’ve written it off as my body being sore from whatever exercise I did that week, but this no longer seems like a viable excuse. Other notes: I am extremely hyper-flexible in my knees and elbows, I’ve heard EDS thrown around by one of my doctors but don’t have a formal diagnosis. Also I don’t drink alcohol pretty much ever, but on the rare occasions I do, my knees get hotter and achy, and I’ve learned I can no longer drink wine at all because I get by far the worst reaction from it. If anyone has any advice for things to test for, I’d really appreciate some new ideas. Thank you guys. Edit: just to show you guys what I take Everyday: Fish oil B vitamin complex Low dose tadalafil Amino acids Then I cycle through maybe a dozen other things every 2 weeks to keep my daily load manageable, and still take BPC-157 when I do high impact exercise Edit 2: I’ve had Ozone and PRP injections into my knees and back injury summer of 2025 (to help treat a back injury and help with whatever’s going on with my knees). It helped significantly with my back, but was marginal at best for my knees
Reddit · r/BiohackersHelped partially · mildoral and injectableover 104 weeks
it definitely helped for a while, especially when taking after particularly intense exercise for recovery
@Top_Buy2467·Reddit UserSource ↗
r/Biohackers · Comment
@NegotiationWaste5815
I used the oral 250mcg capsules manufactured by Freedom Reasearch for approximately 2 months. I was using it to help with my knee recovery after a minor lifting related injury. During that time that was the only supplement I was taking for it. While I did notice improvement, it wasn't outside the range if something that I couldn't attribute to placebo. However, this is a relatively short timeframe. Cost is a hurdle in taking it long term. I've heard that the results are better when getting this via injection for soft tissue/light injuries.
Reddit comment · r/BiohackersHelped partially · mildoral 250mcg capsulesover 8 weeks
I did notice improvement
@NegotiationWaste5815·Reddit UserSource ↗
YouTube comment
@mikelake4640
If you have never taken any of these things in your life and you have a knee injury and shoulder and so on from a life time of body building, what would be the dose to start, do you front load it for a week or so and then just do a maintenance stage? I have a bottle of both of them combined.
YouTube commentInconclusive
knee injury
@mikelake4640·Youtube CommenterSource ↗
YouTube comment
@chad3034
Just ordered the 20mg blend BPC157 / TB500. Was looking to take 500mcg a day for knee & back injury. I noticed you mentioned vial was 10mg blend but you still put 5mg in calc? Thoughts on the 20mg blend for calc input on the mg side?
YouTube commentInconclusive500mcg a day
knee & back injury
@chad3034·Youtube CommenterSource ↗
YouTube comment
@AndrewMiller-rm4fp
Is there any benefit to taking BPC 157 and TB500 if you’re not dealing with a significant injury? I have some minor issues like back pain and knee discomfort, but I’m considering them for overall health and recovery. What are your thoughts?
YouTube commentInconclusive
knee discomfort
@AndrewMiller-rm4fp·Youtube CommenterSource ↗
YouTube comment
@augustmosco
Good, honest video, thanks. I, too, have a few chronic injuries that I would like to alleviate. I have a torn MCL with a ruptured Medial Meniscus that never healed right. On my other knee, I have a traumatized Semimembranosus Tendon (the tendon that attaches the hamstring to the back of the knee) and I have an old Bicipital Tendon injury. I started taking BCP-157 (1000mg) orally, 18 days ago with no improvement as of yet. I'll continue for 60 days. Let's see if this works. I'll certainly get back to you.
YouTube commentInconclusive1000mg orallyover 0.43 weeks
no improvement as of yet
@augustmosco·Youtube CommenterSource ↗
YouTube comment
@danreder8985
I am not having any bad reactions, my gut health is fantastic which is a bonus, my feet omg they feel great snd i work as warehouse manager during the day ( 8hrs) and ups at night ( loading trailers) so i work a ton! I had torn rotator cuffs ( both sides) which i treated with PrP injections and the sports medicine place i went to said the only thing that could improve the results would be Testosterone to which i qualified for TrT as my levels were @180 as a 40 yr old . I stsrted with pelleting but my levels would go up to 1400 and then drop dramatically so i switched to weekly shots which keep me between 700-900. I was feeling great but beat up from constant wear and tear and the TrT dr. i go to recommended bpc157 but tried selling me the oral which was like 150$ a month which i cannot afford. I did research online and all the " bigger guys " im 6"5 210 pounds recommended do stomach injections. And 250ml a day or x2 a day ,but to also do a full 5mg bottle on 1 shot and then micro doae the 250 -500ml a day? I thought that was crazy not knowing if i would have side effects so i started the 250 and increased to 500ml. I didn't know it effected your mood and i have 💯 been way more mellow on the trt then i was before the bpc which is another unintentional good side effect but im waiting on the knee pain which is getting horrible again with cold weather as i have bruisitis and tendonitis in my arms in which the one arm its gone down to my thumb , actually in both but the one feels better. Ive been on for a solid month now , im glad I saw the videos saying it does not matter if you shoot into the spot of pain as i didnt want to look like a heroin addict with track marks on my arms!!! But im wondering if i need to increase the dose, try new source ( peotide tech is where i ordered but they had good reviews) of if i need to just keep going with it. Or if i just work too much!!! But not working is NOT AN OPTION. I see people recommend the bpc157 combo with that 500 stuff? Should i press on? Is that massive monthly shot just a horrible idea? Please 🙏 help me out. As i said im definitely getting results , i get my blood work done every 2-3 months and my kidney function/ blood flow and all that is fantastic since starting. I just need recovery! I only can sleep 4-5 hours a night though but i have option to nap for an hour or two during the day but another thing i noticed is im not napping or wanting to as much the past week or so which is about the 1 month mark? Any information or advice eould be great im so worried about the winter coming with the brusitus as im in northern Illinois and the swings in temp for below freezing to above literally make me wanna cry in the morning Thanks
YouTube commentInconclusive250-500ml/dayover 4 weeks
I'm waiting on the knee pain which is getting horrible again
@danreder8985·Youtube CommenterSource ↗
YouTubeInconclusiveThin evidenceintraarticular injection
17 participants with knee pain received BPC-157 injections
YouTube comment
@xeroxboy01
I'm on day 22 of bpc at 500 mcg and haven't felt any different. I've had a bruised palm for almost 2 months and it hasn't helped with that or my knee pain. Got my stuff from peptide science.
YouTube commentDidn't help500 mcgover 5 weeks
hasn't helped with that or my knee pain
@xeroxboy01·Youtube CommenterSource ↗
YouTube comment
@rCrypto_Frog4148
imma try it for a couple months cuz i just knee issues. I lift heavy and no matter how long my breaks are, even after 2 months my knees feel inflamed.
YouTube commentDidn't help
knees feel inflamed
@rCrypto_Frog4148·Youtube CommenterSource ↗
YouTube comment
@emo1817
Did it help u. I just starting using 20iu every other day. I don’t see much difference with my knee pain. Any recommendations? Thnk u
YouTube commentDidn't help20iu every other day
I don't see much difference with my knee pain
@emo1817·Youtube CommenterSource ↗
YouTube comment
@LeonardoCubillos-f8i
I ran the Wolverine stack systematically in the morning and took BPC-157 at night, 250 mcg in each knee (1 mg total per day). It didn’t seem to help me. After running some tests—which showed no major issues—my orthopedic did a single injection of hyaluronic acid in each knee last week. I’m still resting, but my knees felt significantly better the next day. My knee issues were mostly from running
YouTube commentDidn't help250 mcg in each knee (1 mg total per day)
It didn’t seem to help me
@LeonardoCubillos-f8i·Youtube CommenterSource ↗
YouTube comment
@ZacKabot
I’ve had knee pain from running that hasn’t gotten better over a couple years and diagnosed with patellafemoral pain syndrome that has not healed with PT. Been to three PT’s. Will oral bpc 157 help this injury. Whenever I start pt strengthening quads my knees can’t handle it.
YouTube commentDidn't help
knee pain from running that hasn’t gotten better
@ZacKabot·Youtube CommenterSource ↗
YouTube comment
@cynthiaczarnecki5831
Question about the front loading of TB500. You mentioned you did 5mg daily and then cut back by 50% each week. In the diagram it stated 5mg -- 2 x per week? just little confused cause I seem to have re--injured my knee somehow even with a meniscal cleanup a year ago again. I want to try this protocol, just want to clarify before I inject 5mg everyday ( Mon-sun) Thank you David for great content always....
YouTube commentDidn't help
re-injured my knee somehow even with a meniscal cleanup a year ago
@cynthiaczarnecki5831·Youtube CommenterSource ↗
r/Biohackers · Post
@Nepolax
Bpc 157 weird side effects
I started taking 250mcg/day a week ago and I got random upper back pain 2 days after. I have never had issue an issue with upper back and havent even worked out in 2 weeks. Now its been a week and my neck and upper back is killing me. Also, my knees have gotten so weak that when I walk I feel the road hit my knees. I wear contacts and my eyes are painful to touch. I am starting to think this might be bpc’s reaction. Im getting off this drug from today. I hope this reverses.
Reddit · r/BiohackersDidn't help250mcg/dayover 1 week
my knees have gotten so weak
@Nepolax·Reddit UserSource ↗
r/ChronicPain · Comment
@kifferella
Yeah, I'd buy that out of Ottawa Hospital. Five years ago, i got my hips replaced there. They were so disintegrated that at that time, I was on 30mg twice a day ER morphine, and six 5mg as needed quick release pills for breakthrough pain. Took me nearly two decades to get up to that, but that's what it was back then. I was told that my meds and dosages were part of my records, known and understood. I didn't need to bring anything from home because they would be covering my med needs during the few days I recouped in hospital. So the morning after the surgery, they brought me a single 5mg IR pill. I told them I didn't generally take those unless my actual dose wasn't really doing it. They said this was all I'd be getting. It's standard! Ok, but I've got meds I take that should be on my chart and was told not to bring anything and that everyone on the ward would know? We have no earthly clue what you're on about. If you're still in pain in five hours, you can have 2mg IV morphine. Cool. Only 27mg short of the dose I was repeatedly told I'd be given. But sure, Jan. Luckily im not fucking stupid and they've done this shit to me every time I've been hospitalized ever. So I brought my pills. I swear the nurses seemed confused and annoyed i wasn't freaking out. Meanwhile they bring in this little old lady who'd slipped on the sidewalk and smashed her knee. For two days I listened to her moan in pain and terror and beg for the only med that ever worked for her without giving her nausea and headache. Codeine. Just a tec-3. That's all she wanted. They offered her Percocet. Vicodin. Morphine. Oxy. She refused them all since they just made her vomit and feel sick. So they left her like that. Wrote that she refused meds and left her for DAYS waiting for surgery with broken bones, completely unmedicated. A pharmacy rep toured the ward and was just gosh darn so surprised I felt any sort of way about being obviously lied to, and being forced to watch a woman suffer. I told her if I was at all mobile, I'd have just gone down to the commercial pharmacy in the lobby and bought the lady a bottle of tec-1s since they dont even need a prescription, and that not for a fucking instant did i believe a major metropolitan hospital "didnt have" tec-3s. Someone somewhere decided to fuck that woman over, for their own reasons, and it was disgusting and immoral. Those people will give you that lecture even if you've got a broken bone hanging out. It's a power and control thing, disguised as a moral and judgement thing. But for most of us, the part where we learned to lean away from our experience of our pain happened within the first decade of having it. It's not new news, and it's only the answer if the pain was only in your head. And since the medical professionals dont give a fuck which one it actually is...
Reddit comment · r/ChronicPainDidn't helpcodeine
All she wanted. They offered her Percocet. Vicodin. Morphine. Oxy. She refused them all
@kifferella·Reddit UserSource ↗
r/ChronicPain · Post
@WirelessChimp
This is being too much and I'm just 32.
Hi, one more guy struggling here. I don't really know how to start (also English isn't my native language but I'll try to get over it). I guess it all begun the day I was born, not kidding. I came here with a very big hole on my heart (ventricular septal defect) that should be treated through surgery on a life-death gamble, when I was just 7 months old. Turned out I won, but no one could anticipate the problems I will have in the very distant future once the heart-related stuff went off (which they didn't completely, but at least enough to let me live a normal life). Here comes the real suffer, where I'm still stuck: At the age of 12 (more or less), while growing quite fast physically, the doctor detected two new problems: I was developing scoliosi, with a significant pattern, since it was at the superior part of the back and oriented towards my heart (like if it wanted to surround it), and at the same time I was diagnosed with mild cardiac insufficiency, which I think wasn't that surprising since my heart always did that heart murmur that still does today. The first years, let's say up to my 16-17, I wasn't really haven't any problem. I was physically very active though, which helped a lot. After that I felt on a depression for many reasons that I think it would be pointless to go deep on them, but there's a few: self-esteem problems, alcoholic parent, living in a toxic little town and so on... Mix this with the fact that I'm diagnosed with giftedness since I was a kid, which means my mind is a storm of thoughs 24/7 that I'm not always strong enough to handle (another thing for another topic though). It was at this time when the consistent pain begun. It kinda come and go, and was focused sometimes on my lower back, sometimes on my upper back or even on my chest, like if it was surrounding the heart, which is exactly how I feel right now while writing it (well, in fact, even worse, since I'm struggling with my neck and other parts, but I'll go deep on this later). From this age til today, It has become way worse, beginning to rise to some serious levels of pain at the university (around 21-24 years old back then). To begin with, I can only sleep looking at the ceiling, not sided. My pain made it impossible most of the time, unless I'm so exhausted that I can sleep on any position. At the age of 27 I got a fantastic lucky strike. Just starting my holidays literally 30 minutes ago, a drunk guy did an illegal movement and crash with the car I was in, just when we where about to stop the car (luckily we where in a town, so it was a """"slow"""" crash). No one died, but I was so "lucky" that I got the worse part, since the vehicle crashed towards my window ( I was on the back seats) and although instinctively I tried to protect myself rising my left arm, it obviously wasnt enough to prevent a terrible pain and temporal suffocation since my rib cage was momentarily compressed. I went through a terrible month of pain and opiates. Literally laughing was something I couldn't handle. Now I'm 32 and things have gotten way worse. I have an specific point on my back and chest where the pain focuses and reaches its peak: it begins on the left scapula and goes through to my chest drawing an imaginary diagonal that feels like if you were stabbed on your back. Constantly. I usually cry, when depressive rollercoaster goes on. Recently I took an overdose of diazepam after an argument with someone important for me, just because I wanted to stop the situation of physical and psychological pain simultaneously. I didn't want to die, but I did not care either, to be honest. I just wanted the pain (in big terms, both physical and mental) to stop and literally did not even care if I die. Maybe its not easy to understand the process I went through at that moment, but I didn't thought something like "no one loves me and I'm absolute trash, I want to die". It was more like "this is an unspeakable pain, outside and inside, I just want it to stop right now, and I don't really care about the output as long as it stops". So I slept like a baby this night, but I think I should be scared (my family was and its my fault) because I found myself on a situation where I rationally decided that it was worthy to take the risk of an overdose to get out of the painful situation. I wasn't crying desperetely for help or something similar, I was just full of pain and frustration, even in form of fury, a feeling that has never been common on me (in fact, people tend to say that I'm very calm). Recently I've been fired illegally (that's another story, based on how much of a psychopaths bosses can be) and I have to go through the whole process of reporting the company, which increases my physical pain (and then, the psychological) even more. I can't remember the last time I haven't pain on my upper back and/or neck. I went to some physical therapies that helped me, and I want to go again, but turns out they are expensive and I'm just a poor worker in a poor country like Spain -don't let anyone fool you with the "being a member of European Union" thing-. During those therapies I understood the role of my surgery as a baby and the accident when it comes to back pain. I mean, knowing this did not help with the pain itself, but it made a lot of sense since my body is literally curving towards the heart like attempting to protect it from terrible situations it already went through. Nowadays, I can have pain on nearly every part (not simultaneously, though) of the left side of my body -in fact, my body is "higher" on the left side, than the right side, as consequence of all this-, til the point that I had to "retire" from football recently because my left knee is giving me constant pain, which is funny since I have 0 weight problems that could be related with that, I mean, my knee never had to support a lot of weight, I'm 1.8m tall and weighted 65-70 kg my entire adult life (and comparable values while being a kid). I have ¿fear? (I don't know if this is the word, since I'm not scared) that someday I may just had enough of all this struggle. In fact, I can't imagine 32 more years of this. Not even 10, to be honest. I'd like to keep going with my dreams (I have goals, like working hard to own a house, and a life with my girlfriend. I have hobbies since I like to code, playing football, playing chess, practice astronomy, being with my friends, being close to my beloved mother...) but I don't know for how long I could still rationally choose that all of them are worthy enough to keep myself tanking this pain. In fact, I'm crying right now while holding an imaginary backstab on my left side and another one on my neck. It's not a desperate cry of someone going through a very deep sorrow caused by a recent event of any nature. It's just desperation and being emotionally exhausted because I'm physically exhausted. Thanks if someone read til this point, specially with my messy English. And if not, I completely understand it, I just wanted to scream for a while and I've chosen this place, this time. ​ TL;DR : Chronic pain is a life sentence. Don't know how much time I may handle it.
Reddit · r/ChronicPainDidn't help
my left knee is giving me constant pain
@WirelessChimp·Reddit UserSource ↗
What the science says

Related research

All papers →
Review· nulllow
2026

Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.

This review of injectable peptide therapy found that while BPC-157 and other peptides show potential for tissue repair and regenerative medicine, there is a lack of evidence to support their clinical use, particularly in human trials. The review concludes that more research is needed to determine the safety and efficacy of these peptides.

The American journal of sports medicine· Mayfield CK, Bolia IK et al.
PubMed · PMID 41476424
Review· nulllow
2025

Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing.

BPC-157 demonstrates robust regenerative and cytoprotective effects in preclinical studies, but human data is extremely limited, with only three pilot studies conducted. The review concludes that BPC-157 should be considered investigational and its use approached with caution until well-designed clinical trials are conducted.

Current reviews in musculoskeletal medicine· McGuire FP, Martinez R et al.
PubMed · PMID 40789979
Review· nulllow
2025

Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review.

This systematic review suggests that BPC-157 shows promise for promoting recovery from musculoskeletal injuries, with preclinical studies showing improved functional, structural, and biomechanical outcomes in muscle, tendon, ligament, and bony injuries. However, the review highlights the need for further clinical safety data and notes that adverse effects are possible due to unregulated manufacturing or contamination.

HSS journal : the musculoskeletal journal of Hospital for Special Surgery· Vasireddi N, Hahamyan H et al.
PubMed · PMID 40756949
Case report· humanlow
2021

Intra-Articular Injection of BPC 157 for Multiple Types of Knee Pain.

This study found that intra-articular injection of BPC-157 helped relieve knee pain in 87.5% of patients with various types of knee pain. The study suggests that BPC-157 may be a useful treatment for multiple types of knee pain.

Alternative therapies in health and medicine· Lee E, Padgett B
PubMed · PMID 34324435