General Gut Inflammation
Of the 20 unique stories with a clear outcome, 16 reported it helped (80%). 3 were inconclusive.
These are public YouTube testimonials, not clinical evidence. People who tried BPC-157 and got no result rarely post videos — read this as a sample of the positive end of the distribution.
I used BPC-157 from life link after getting stomach problems, took me like 3 weeks to notice my gut wasn’t acting up much. Glad you bring up joints too, cause i think it helped my knees from all the running. Keep sharing more about recovery, real helpful info.
“my gut wasn’t acting up much”
Taking oral bpc 157. Only take it about twice a week. The missing after i feel like inflammation is flushed out of my body.
“inflammation is flushed out of my body”
I used BPC-157 for about five weeks because I couldn’t tolerate supplements like Tongkat Ali, Cistanche, or even boron anymore. They caused loose stools and stomach cramps. I decided to take BPC-157 daily for four weeks along with probiotics. I had tried probiotics on their own before, but they didn’t help. After about two weeks, my loose stools were gone and I could take supplements again without any issues. I then stopped the probiotics but continued BPC-157, and the results stayed the same. After about a month of using BPC-157, all my digestive issues were completely gone. The only supplement I still can’t tolerate is Fadogia agrestis, but I’ve accepted that.
“all my digestive issues were completely gone”
Hello from SW Florida. My peptide injections come today. I ordered from Oath in USA. I have the insulin syringes. I wanted ask if they can be layered or segmented in admin reason I ordered bp 157 and epthalon and NADplus and aod9604 . Jmho I feel the pills work but I doubled up the size and it takes several weeks ...I been on the pills for two weeks twice daily and seeing reduction in inflammation. I'm an ex RN (retired) who hates big pharma and Western medicine! (Which this accident btw has me immobile and in a wheelchair after an accident so I am desperate to get better) ❤ I been in horrible pain for two years and all western med want to do is replace parts ... 😮 I also just got a large supply of glynac ...
“seeing reduction in inflammation”
This is exactly the kind of content I've been searching for! I started a BPC-157 and TB-500 protocol about 3 months ago after struggling with gut inflammation and an old knee injury, and the difference has been remarkable. Learning about GHK-Cu and KPV here just made me want to add the full glow stack - Dr. Froese explains everything so clearly without the intimidating jargon. I actually sent this to my functional medicine doctor right away. Thank you so much for this!
“the difference has been remarkable”
I am using UritholinA w my oral BPC-157 from ProHealth compound pharmacy for my stomach healing and intestinal inflammation also recovery from cervical n upper back fusion surgery C2-T4
“stomach healing and intestinal inflammation”
I got anhedonia via BPC-157, but it healed brutal GI issues that messed up more than half of 2023. Was totally worth it
“healed brutal GI issues”
Peptides are the REAL DEAL. I use CJC-1295 DAC + Ipamorelin and within 2 weeks, the weights I was using on the machines suddenly didn't feel like enough to get a workout. I was amazed. Nothing crazy, but I have now moved up in weight for my normal workout. And I am 63 years old. I will add that you MUST do some kind of resistance training if you ae going to do these peptides. The GLOW peptide WORKS. My hair is actually returning to its original brown color. Inflammation is way down.
“Inflammation is way down”
I am not having any bad reactions, my gut health is fantastic which is a bonus, my feet omg they feel great snd i work as warehouse manager during the day ( 8hrs) and ups at night ( loading trailers) so i work a ton! I had torn rotator cuffs ( both sides) which i treated with PrP injections and the sports medicine place i went to said the only thing that could improve the results would be Testosterone to which i qualified for TrT as my levels were @180 as a 40 yr old . I stsrted with pelleting but my levels would go up to 1400 and then drop dramatically so i switched to weekly shots which keep me between 700-900. I was feeling great but beat up from constant wear and tear and the TrT dr. i go to recommended bpc157 but tried selling me the oral which was like 150$ a month which i cannot afford. I did research online and all the " bigger guys " im 6"5 210 pounds recommended do stomach injections. And 250ml a day or x2 a day ,but to also do a full 5mg bottle on 1 shot and then micro doae the 250 -500ml a day? I thought that was crazy not knowing if i would have side effects so i started the 250 and increased to 500ml. I didn't know it effected your mood and i have 💯 been way more mellow on the trt then i was before the bpc which is another unintentional good side effect but im waiting on the knee pain which is getting horrible again with cold weather as i have bruisitis and tendonitis in my arms in which the one arm its gone down to my thumb , actually in both but the one feels better. Ive been on for a solid month now , im glad I saw the videos saying it does not matter if you shoot into the spot of pain as i didnt want to look like a heroin addict with track marks on my arms!!! But im wondering if i need to increase the dose, try new source ( peotide tech is where i ordered but they had good reviews) of if i need to just keep going with it. Or if i just work too much!!! But not working is NOT AN OPTION. I see people recommend the bpc157 combo with that 500 stuff? Should i press on? Is that massive monthly shot just a horrible idea? Please 🙏 help me out. As i said im definitely getting results , i get my blood work done every 2-3 months and my kidney function/ blood flow and all that is fantastic since starting. I just need recovery! I only can sleep 4-5 hours a night though but i have option to nap for an hour or two during the day but another thing i noticed is im not napping or wanting to as much the past week or so which is about the 1 month mark? Any information or advice eould be great im so worried about the winter coming with the brusitus as im in northern Illinois and the swings in temp for below freezing to above literally make me wanna cry in the morning Thanks
“my gut health is fantastic”
Another superb video! Ive used three, 25 day cycles of Glow since September but as separated peptides rather than a blend and my skin age has reduced noticeably (8-10 years) to the point of many people I know commenting on it without knowing anything about Peptides or what protocols ive used. On top of that, ive had enormous gut health improvements, healing of long term joint injuries and some areas of inflammation just disappear. I have to say ive had an incredible experience.
“enormous gut health improvements”
I’ve been stuck for a while feeling like my brain wanted to go fast but my body wasn’t keeping up. Joints heavy, gut unpredictable, and it was frustrating because I was already eating clean, sleeping decent, stretching… all the “right” stuff. Still felt like my system was stressed out. I came across some actual research on BPC‑157 (not ads). It’s a peptide that’s supposed to help with tissue repair and gut health. Figured it might be worth trying since it works with the body’s own signaling instead of just tossing random supplements at it. Started taking it orally and things felt smoother. Less stiff in the mornings, digestion steadier, recovery from workouts faster. Even a small cut on my hand healed quicker than usual. Could be coincidence, but I noticed it. The biggest change wasn’t just physical, well it was peace of mind. When your body feels solid again, you stop overthinking every rep or meal. Not a magic fix, but more like giving my system better tools to do its job. If anyone else has been dealing with that “made of glass” feeling, the research on BPC‑157 is worth checking out. Here are a few papers I found useful when looking into BPC-157: \- [https://pmc.ncbi.nlm.nih.gov/articles/PMC13026520/?utm\_source=copilot.com](https://pmc.ncbi.nlm.nih.gov/articles/PMC13026520/?utm_source=copilot.com) \- [https://pmc.ncbi.nlm.nih.gov/articles/PMC11859134/?utm\_source=copilot.com](https://pmc.ncbi.nlm.nih.gov/articles/PMC11859134/?utm_source=copilot.com) \- [https://pmc.ncbi.nlm.nih.gov/articles/PMC9794587/?utm\_source=copilot.com](https://pmc.ncbi.nlm.nih.gov/articles/PMC9794587/?utm_source=copilot.com)
“digestion steadier”
Disclosure, I am not a doctor and ALWAYS consult with a LICENSED doctor and or physician before taking NSAID’s and other listed supplements as described in this post. My Diagnosis: H-EDS. Hyper Mobility- Ehlers Danlos Syndrome. I also have adhd and anxiety, other than those I’m healthy lol, at least to my knowledge 😳😂😂. Post Follows: Just a tip- You guys always need to make sure you eat BIG before taking NSAID’s. I literally take 4-6 Advil Liqua-Gels a day and as long as I eat BIG and HEALTHY meals before… I NEVER have a problem with my stomach. I KNOW, 4-6 pills is ridiculous and should not be taken under any circumstances without doctor opinion. Well actually… the best option is to just not do any BUT, for most Advil is the ONLY thing that makes us feel normal. This is for everyone, U guys can’t just pop these things on an empty stomach and expect nothing. It’s literally eating your liver lining because there is nothing stopping it from doing so. Food is the answer my friends. Not just a yogurt and pop the pill. I’m talking a nice full meal! Inflammation Treatment Guide: Disclosure, I am not a doctor and ALWAYS consult with a LICENSED doctor or physician. List begins: Try Creatine supplements from your local GNC or Vitamin Shoppe. ALWAYS drink a gallon of water EACH day when taking Creatine to protect against kidney damage. With increased water consumption and the wonderful FDA approved benefits, Creatine will possibly make you feel better. Also stop eating McDonald’s or any of that crap, once in a while okay but that stuff even weekly can have some pretty gnarly consequences to your mental and physical health. Also try cannabis! Be very slow and small with dosing. I’m talking like a 2 second hit from a blunt, waiting to see how it feels after 30min-1 hour. And then slowly going up in hits. Marijuana can hit you like a train in a very uncomfortable way if u do too much on the first time. Better yet, instead take a nibble of an edible. Like bite the corner off a 10mg one from the dispensary. And go up from there. That stuff helps me with my inflammation and my depression/anxiety from dealing with pain everyday. LASTLY TRY HOT SHOWERS, THE BEST. Play your favorite music and just let the water hit the spots that hurt. Stay in there for 20 min, FUCK the water bill 😂. I work so fucking hard on finding solutions to the pins and needles that my body throws at me everyday. I hope I can change someone’s life for the better!🤍 Edits: Grammar and personal diagnosis
“I NEVER have a problem with my stomach”
Disclosure, I am not a doctor and ALWAYS consult with a LICENSED doctor and or physician before taking NSAID’s and other listed supplements as described in this post. My Diagnosis: H-EDS. Hyper Mobility- Ehlers Danlos Syndrome. I also have adhd and anxiety, other than those I’m healthy lol, at least to my knowledge 😳😂😂. Post Follows: Just a tip- You guys always need to make sure you eat BIG before taking NSAID’s. I literally take 4-6 Advil Liqua-Gels a day and as long as I eat BIG and HEALTHY meals before… I NEVER have a problem with my stomach. I KNOW, 4-6 pills is ridiculous and should not be taken under any circumstances without doctor opinion. Well actually… the best option is to just not do any BUT, for most Advil is the ONLY thing that makes us feel normal. This is for everyone, U guys can’t just pop these things on an empty stomach and expect nothing. It’s literally eating your liver lining because there is nothing stopping it from doing so. Food is the answer my friends. Not just a yogurt and pop the pill. I’m talking a nice full meal! Inflammation Treatment Guide: Disclosure, I am not a doctor and ALWAYS consult with a LICENSED doctor or physician. List begins: Try Creatine supplements from your local GNC or Vitamin Shoppe. ALWAYS drink a gallon of water EACH day when taking Creatine to protect against kidney damage. With increased water consumption and the wonderful FDA approved benefits, Creatine will possibly make you feel better. Also stop eating McDonald’s or any of that crap, once in a while okay but that stuff even weekly can have some pretty gnarly consequences to your mental and physical health. Also try cannabis! Be very slow and small with dosing. I’m talking like a 2 second hit from a blunt, waiting to see how it feels after 30min-1 hour. And then slowly going up in hits. Marijuana can hit you like a train in a very uncomfortable way if u do too much on the first time. Better yet, instead take a nibble of an edible. Like bite the corner off a 10mg one from the dispensary. And go up from there. That stuff helps me with my inflammation and my depression/anxiety from dealing with pain everyday. LASTLY TRY HOT SHOWERS, THE BEST. Play your favorite music and just let the water hit the spots that hurt. Stay in there for 20 min, FUCK the water bill 😂. I work so fucking hard on finding solutions to the pins and needles that my body throws at me everyday. I hope I can change someone’s life for the better!🤍 Edits: Grammar and personal diagnosis
“that stuff helps me with my inflammation”
30yo male here. Had pretty bad insomnia since I was 18. Here's a TLDR; for those that don't want to read the wall of text below: 10 years of life disrupting insomnia, 2 years of life ending insomnia. Have taken nearly all available prescriptions to try to sleep. Few worked, all came with side effects eventually that worsened my health. While trying to repair the damage that chronic multi-day long sleeplessness created, I stumbled upon a cheap and readily available cure for all of my issues including my insomnia. A peptide called GHRP6. I would put it under my tongue at night, eat a huge meal, and then become intensely tired. First time in my adult life I slept like a fucking rock. It has been 4 months and it has been only consistent success. Totally safe to take for as long as you want. And comes with the added benefit of increase healing, anti-aging, etc. --------- I have two main causes of my insomnia, basically. First is, I have racing thoughts. Will replay the day, the past week, year, decade, etc in my head. Can't clear my mind and fall asleep. Second, I have a crazy adrenaline response. If I hear a noise, my adrenaline spikes and my heart pounds. If I am having trouble falling asleep, then I get nervous that I am going to have a shitty day the next day, so then my heart start racing and then I don't sleep because of it... etc. at 22yo I took trazodone and it definitely made me sleep if I stayed with an ever increasing dose. It gave me brain fog, short term memory issues, a few other side effects which were serious enough to where I had to get off of it. I started taking vyvanse for work after I graduated college, and it did not worsen my insomnia from what it was until about age 26. At age 26, I would go atleast 1 night a week without sleeping at all, and then a few days with 4-5 hours of sleep. The vyvanse made it to where it wasn't really an issue to deal with though. At 27 I got on Ambien, then lunesta, hydroxizine, a few other benzos, amitriptyline, and a few others. Lunesta was the only one that did anything, and I slept well for a while. It eventually stopped working, and about 16 months ago, I went into a serious dark bottomless pit of insomnia. At 29, roughly 16mo ago, I went through a period of time, while on lunesta, where I wouldnt sleep for up to 5 days. Not your typically, rolling around, falling in and out of a shallow sleep and then telling people you didnt sleep at all ... I mean stare at the fucking ceiling for 5 hours and then get up and go to work, for 5 days in a row. This lasted for about 4 months until my body and brain gave out on me. I developed an anxiety disorder. I had lost like 20lbs. I had circulation issues. Stomach ulcers. gastritis. IBS. I couldn't focus at all. I couldn't work. I focus first on the anxiety issues, which lead to SSRIs and SNRIs which made everything 1000 times worse. My sleeping became worse. etc. So then I switched to trying to treat the gastro issues. After diagnosing stomach ulcers and gastritis and IBS, they put me on PPIs and a few other things, none of which helped. Only made it worse. So I did a bit of my own research and came across a few medical studies on peptides, which led me to BPC 157 which is a peptide for healing. This helped briefly, but wierdly enough, it made me sleep very well for about a week then it went away. So after that semi successful run of a peptide I bought off the internet. I looked into others. I read another medical journal about GHRP 6, which is a mimic of a peptide your body creates that tells your body when its hungry and ready to eat. It also helps release your own human growth hormone. I started taking that in order to help stimulate my appetite and bring blood flow to my GI tract and initiate healing. And it worked like a fucking charm. I was eating more than I had in forever, and my stomach issues were rapidly improving. But the one thing that increased more than anything else..... MY SLEEP. Before I started these peptides, I got off sleep medicine, because any pill was hurting my gastritis. I obviously struggled with that and dealt with worsening insomnia, but I pushed through it. I upgraded the course of GHRP6 that I was taking to include another peptide that further increases your own human growth hormone production, called CJC1295 (no dac), and have been taking those two 1-2 times a day for the past 3-4 months. I am back on my vyvanse, I also drink caffeine again (which I quit for 7 years due to insomnia), and I am sleeping better than I have in my whole life. I actually get tired at night, I lay down, and I am out. I may wake up to piss or eat a snack, but back to bed until proper rise-n-shine time. I have been working out for the past 4 months, which is something I havent done consistently in 7 years due to no having the energy and not being able to drink caffeine. I have gain ~30lbs back that I lost from my rock-bottom era 16 months ago. The best part is, this peptide is something that you can take for as long as you want. It does not downregulate your own ghrelin or GH production and you do not develop a tolerance for it. And the cherry on top is, your growth hormone blood levels are increase to 3-4x their normal levels, so your skin is younger, hair is longer and thicker, nails are more healthy, your body heals faster, and your muscles in theory repair faster. It basically makes you feel younger. - Would also like to give a shout out to Clonidine and Guanfacine. Those are 2 medicines that are called alpha-2 adrenergic receptors. They are technically blood pressure medicines, but they are also prescribed for ADHD. They also happen to boost your own natural human growth hormone. I started taking them a few months back, and they tone down my adrenaline response. At the beginning of this post, I mentioned that my adrenaline response was too strong and it kept me up at night with a beating heart. This eliminates that and calms my mind. Really helps with the whole insomnia thing. Feel free to message me about any questions.
“my stomach issues were rapidly improving”
“gut symptoms that nothing else touched begin to resolve”
Hey, I’m trying to figure out if anyone has had a similar reaction because this was honestly pretty intense. I started a KLOW stack. I reconstituted with 3 mL BAC water and was dosing around 10 units.(insulin syringe) I add a tiny bit of bac water to help with the copper burn usually 0.5. Day 1: Started getting pretty bad diarrhea and cramping: \\- repeated “waves” of diarrhea where I’d think it was over, then suddenly have to run again \\- severe cramping (coming in waves) \\- felt like my gut was empty but still spasming \\- bloating + pressure afterwards Day 2: Pretty much the same again, but I took more medication to try and stop it. It was bad enough to wake me up during the night. I took loperamide on the first night, then loperamide + Buscopan on the second. It helped a bit, but the symptoms kept coming back in waves for hours. I also re-dosed while I was already reacting, which probably made things worse. Today (after night 2) I feel ALOT better still slightly uncomfortable but no more runs lol Questions: \\- Has anyone had this kind of GI reaction from KLOW or similar stacks? \\- Was it more likely GHK-Cu (histamine-related?) or BPC-157 affecting gut motility? \\- Did lowering the dose help, or did you have to drop part of the stack entirely? \\- How long did it take your gut to fully go back to normal? I know peptides affect everyone differently, but this felt way more extreme than what people usually describe. Any insight would be really appreciated
“Today I feel ALOT better still slightly uncomfortable”
I have bpc157, KPV and GHK-CU I have had bad digestive issues for some time diverticulitis flare ups and inflammation in small bowel. I will update everyone on how my progress goes over the coming weeks if anyone is interested.
“bad digestive issues for some time diverticulitis flare ups and inflammation in small bowel”
Where can you get the oral form you trust in Canada? I suffer from all kinds of gut issues and my doctors keep telling me nothings wrong with me that I just have gerd and ibs. Nothing they’ve given me has helped and I’ve heard nothing but positive results with bcp 157.
“I suffer from all kinds of gut issues”
I have just started oral BPC157 , KPV and GHK-Cu. I have had bad gut issues for last 3 years, I have inflammation and diverticulitis. I will update on here regarding my progress. Going to try for 6-8 weeks.
“bad gut issues for last 3 years, I have inflammation and diverticulitis”
I have a friend who is suffering from dysautonomia. Do you think peptides can help her? Which ones? She is currently on 13+ medications which I think are contributing to many of her gut issues plus other symptoms. Not much is known about this disease so any help you can give would be greatly appreciated. Thank you! Another question re my use of the Wolverine Stack which I'm using for recent carpal tunnel release surgery and extreme pain from tarsal tunnel syndrome. As well as some gut issues. I do get light headed for about two hours after my injection and will most likely reduce dosage. However, I still have GERD. If I'm injecting, what amounts of oral BPC-157 should I take? Thanks once again for all your very helpful content.
“still have GERD”
Thanks for sharing your journey. I’m amazed what you been through and your recovery. It’s truly a blessing. The improvement in your gut is very positive news. I think your gut and digestive system play a major role in your overall health and your state of mind. I know I’m miserable when I’m dealing with gut issues. I also agree with you on your discussion about the effects of chemotherapy. I’m hoping the best for you and looking forward to further update! Stay strong brother!
“I'm miserable when I'm dealing with gut issues”
500mcg of BPC-157 oral (Infiniwell brand) use for a week gave me the worst anxiety, bloating, headaches, and gut pain of my entire life, about a week ago. It’s been a week since I stopped and I have not fully recovered yet. I’m not saying it’s bad for everyone, microbiomes are unique, and perhaps subQ would have been different—but just throwing it out there, that I’ve never regretted ingesting a substance more.
“gut pain of my entire life”
Hey, I’m trying to figure out if anyone has had a similar reaction because this was honestly pretty intense. I started a KLOW stack. I reconstituted with 3 mL BAC water and was dosing around 10 units.(insulin syringe) I add a tiny bit of bac water to help with the copper burn usually 0.5. Day 1: Started getting pretty bad diarrhea and cramping: \\- repeated “waves” of diarrhea where I’d think it was over, then suddenly have to run again \\- severe cramping (coming in waves) \\- felt like my gut was empty but still spasming \\- bloating + pressure afterwards Day 2: Pretty much the same again, but I took more medication to try and stop it. It was bad enough to wake me up during the night. I took loperamide on the first night, then loperamide + Buscopan on the second. It helped a bit, but the symptoms kept coming back in waves for hours. I also re-dosed while I was already reacting, which probably made things worse. Today (after night 2) I feel ALOT better still slightly uncomfortable but no more runs lol Questions: \\- Has anyone had this kind of GI reaction from KLOW or similar stacks? \\- Was it more likely GHK-Cu (histamine-related?) or BPC-157 affecting gut motility? \\- Did lowering the dose help, or did you have to drop part of the stack entirely? \\- How long did it take your gut to fully go back to normal? I know peptides affect everyone differently, but this felt way more extreme than what people usually describe. Any insight would be really appreciated
“Started getting pretty bad diarrhea and cramping”
Related research
Stable Gastric Pentadecapeptide BPC 157 as a Therapy of Severe Electrolyte Disturbances in Rats.
This review concludes that BPC-157 has therapeutic potential in addressing electrolyte imbalances, including hyperkalemia, hypokalemia, hypermagnesemia, and hyperlithiemia, by counteracting adverse effects and promoting recovery. The peptide demonstrated comprehensive counteractive effects in various studies, including in vitro and in vivo experiments.
Stable Gastric Pentadecapeptide BPC 157 as a Therapy and Safety Key: A Special Beneficial Pleiotropic Effect Controlling and Modulating Angiogenesis and the NO-System.
This review concludes that BPC-157 has pleiotropic beneficial effects, controlling and modulating angiogenesis and the NO-system, and shows promise in wound healing and counteracting neurodegenerative diseases. BPC-157 also exhibits anti-tumor potential and does not produce corneal neovascularization.
Duodenocolic fistula healing by pentadecapeptide BPC 157 in rats. A cytoprotection viewpoint.
The study found that BPC-157, a stable gastric pentadecapeptide, rapidly induces vessel recruitment and healing in rats with duodenocolic fistulas, leading to closed defects and resolved leakage. All BPC-157-treated rats showed significant improvement, with no fistula leakage, diarrhea, or weight loss, and reduced adhesion formation and intestinal obstruction.
Stable Gastric Pentadecapeptide BPC 157 Therapy: Effect on Reperfusion Following Maintained Intra-Abdominal Hypertension (Grade III and IV) in Rats.
BPC-157 therapy was shown to effectively counteract reperfusion-induced occlusion syndrome and reduce organ lesions and thrombosis in rats with severe intra-abdominal hypertension. The therapy also promoted vascular recovery and reversed previous ischemia-course lesions.