All conditions
BPC-157 for ankle

Achilles Rupture

Of the 1 unique stories with a clear outcome, 1 reported it helped (100%).

These are public YouTube testimonials, not clinical evidence. People who tried BPC-157 and got no result rarely post videos — read this as a sample of the positive end of the distribution.

Verdict
100
% positive
1 helped0 partial0 no help
What people tried
BPC-157 injection
Helped · completeThin evidenceBPC-157 injectionover 4 weeks
complete resolution of the healing of the torn Achilles
What the science says

Related research

All papers →
Ex vivo· ratmedium
2011

The promoting effect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth, cell survival, and cell migration.

BPC-157 was found to accelerate the outgrowth of tendon explants, increase cell survival under stress, and promote the migration of tendon fibroblasts. This is likely mediated by the activation of the FAK-paxillin pathway.

Journal of applied physiology (Bethesda, Md. : 1985)· Chang CH, Tsai WC et al.
PubMed · PMID 21030672
Animal study· ratmedium
2008

Modulation of early functional recovery of Achilles tendon to bone unit after transection by BPC 157 and methylprednisolone.

This study found that BPC-157 improved functional recovery of the Achilles tendon to bone unit after transection in rats by reducing inflammation and promoting new blood vessel formation. BPC-157 outperformed methylprednisolone in this regard, as it did not suppress new blood vessel formation.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]· Krivic A, Majerovic M et al.
PubMed · PMID 18594781
Animal study· ratmedium
2006

Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: Promoted tendon-to-bone healing and opposed corticosteroid aggravation.

The peptide BPC-157 was shown to improve tendon-to-bone healing in rats with Achilles tendon detachment, and also reduced the aggravating effects of corticosteroids on healing. This suggests that BPC-157 may be a useful treatment for promoting tendon and bone healing.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society· Krivic A, Anic T et al.
PubMed · PMID 16583442
Animal study· ratmedium
2003

Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth.

The study found that BPC-157 accelerated healing of transected rat Achilles tendon and stimulated tendocyte growth in vitro. The peptide improved recovery by increasing load of failure, functional index, and promoting collagen formation.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society· Staresinic M, Sebecic B et al.
PubMed · PMID 14554208