Dr. Jin W. Sung·Medical Doctor·—
Can BPC-157 Fix Your Gut and Joints?
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·59.1K views·6:45balancedSummary
The video discusses the potential benefits and risks of using BPC-157, a synthetic peptide, for gut and joint health, and highlights the need for further human trials and caution when using it. The speaker provides information on its mechanisms, potential uses, and dosages, while also emphasizing the importance of consulting a physician and ensuring product purity.
Key takeaways
- 01BPC-157 may improve tissue healing, anti-inflammatory effects, and gastrointestinal protection
- 02It stimulates angiogenesis, upregulates growth hormone receptors, and modulates inflammation
- 03Human studies are limited, and it is not approved by the FDA for human use
Full transcript
Can this peptide called BPC157 heal your gut and your joints? What is it? How do you utilize it? And what are some of the dosages utilized in the clinical setting? So, let's get into this very important video. BPC157 is called body protection compound 157. It's basically penta peptide. It's a synthetic peptide made up of 15 amino acids and I've listed those 15 amino acids in sequence here for you. It's basically a protective protein found in human gastric juices or basically in your stomach. It's naturally occurring. However, the synthetic version has been shown to improve a lot of different conditions. So there have been quite a number of animal studies which show tissue healing, anti-inflammatory effects, gastrointestinal protection and neuroprotective effects. And the way it does this and the mechanisms are that it improves angiogenesis. Angioenesis is basically developing new uh uh capillary beds to an injured area. Okay. and does that by stimulating VEGF, vascular endothelial growth factor. Okay. It also upregulates growth hormone receptors. So you can actually have a heightened impact of growth hormones into that area. Also stimulates ENOS which is endothelial nitric oxide synthes modulates inflammation and promotes the fibroblast. Fibroblast is basically what helps to turn over the cells and rebuild new collagen to the injured areas. Okay. Human studies are very limited. There's some studies on uh IBD and ulcerative colitis. Now, there's some cautions utilizing this peptide. BPC57 has not been approved by the FDA for human use. Okay. Also do not use it if there is concern for cancers or tumor growth because of the angioenesis. Basically you're increasing vasc vascule to a cancer area or tumor cell. So you don't want to do that. There's also issues with quality control because it's not regulated in terms of purity. Okay. Uh you need third-party tested you know products. The other thing is if it's not third tested uh third party tested there can be an increase of what what we call lipopolysaccharides during the manufacturing process. Lipopolysaccharides can be in the product itself. Now lipopolysaccharides can create inflammation if used over and over and over. So I think it's very important that you u utilize BP uh C157 um with a physician who understands this and they can give you or guarantee purity because they use a maybe a compounding facility um to guarantee uh purity. World Anti-Doping Agency also prohibits it. So Olympic athletes can't cannot use it. So delivery methods injectables subcutaneous or intramuscular. So you can take these tiny little needles and put it into the belly fat and you can actually have a very global effect because these peptides will travel to whatever injured areas there are. There's also oral it's called BPC157 arginate salt and those are in capsule form and they actually have uh multiple companies producing this in the oral capsule form. You can also use it topically for wound healing. dosages 500 micrograms per day up to 5,000 micrograms. So, if you're going to use higher doses or even if you're going to use this, I would suggest consulting with the physician who understands this. Um, these are just kind of broad ranges of what's been used clinically or therapeutically. Typically, you use 5 days on and two days off. So, you go Monday through Friday, take Saturday, Sunday off. Okay. BPC157 also has been used with TB500, right? These are also injectables and used together, it tends to have a better impact on wound healing or injury healing. Also, there's been case improvements with postcoid symptoms. So, if you have long COVID or you have issues with um COVID related um health issues, it may be beneficial for that. And now again, there's no real studies on this. It's just been sea seen in cases and in the clinic. If you're going to do this, I would suggest doing a comprehensive blood panel. So CBC or complete blood count, a basic metabolic panel, liver enzymes, lipid panel, inflammation markers like uh C reactive protein or ESR. I would also do a hormone panel to see if there's an impact on hormones. I would also do creatine kynise and LDH to see if there's any muscle damage prior to doing it. So, if you did a basic uh comprehensive metabolic panel uh and blood work before you started and then do the panel afterwards, it would give you a a gauge of improvement or two if there's any problems with utilizing this peptide. So it's important to do all of this. Now there are companies uh that are providing this to clients or patients uh without a doctor's script. Okay. Now you have to be careful of which companies you utilize. You know I would highly suggest working with the physician in order to get the highest quality that you can get. But there are many companies uh that make them and there's also black market you know products out there. Again the problem is purity and the contamination of lipopolysaccharides within the product itself. All right. So this is very promising in the clinical setting. There has to be a lot more human trials in order to be more um what we call common use uh in the public. All right. My name is Dr. Jen Sun. We're clinical excellence meets excellent results and we'll see you guys next week on the healthy side. Have an awesome day.